Product Testing Moves Away from Animals

Posted by Stephanie Ulmer, Guest Blogger on November 21, 2011

It’s about time, right? The Los Angeles Times recently reported that Allergan, the maker of Botox, had a process approved earlier this year by the Food and Drug Administration that will allow Allergan to test its product on cells in a lab dish, instead of having to test every batch on live animals. It took Allergan 10 years for its scientists to develop the test, but its success may allow Allergan to stop at least 95% of its animal testing within three years if the process is approved by all the other countries in which Botox is sold. According to the Times article, “The government says that every new compound people might be exposed to — whether it’s the latest wonder drug, lipstick shade, pesticide or food dye — must be tested to make sure it isn’t toxic. Usually, this requires animals. Allergan’s new test is one of several under development, or already in use, that could change that.”

Joyce Tischler, ALDF’s founder and general counsel, finds the advance a terrific step in the right direction. “One of the most exciting developments in science today is the move away from the use of live animals and toward the use of tissue cultures, cell cultures and other non-animal alternatives. Scientists are exploring a variety of alternatives to the use of animals in testing and this is a significant advance. Not only will fewer animals suffer, but non-animal tests are better predictors of what a human reaction will be, and they are faster and less expensive. It’s a win-win for everyone.”

Testing facilities in the U.S. indeed test on nearly one million mammals per year, according to 2009 statistics from the U.S. Department of Agriculture. But that number does not include mice and rats, the most widely used animals in labs, because the U.S. Animal Welfare Act excludes them. It has been estimated that the actual number of research animals used in the U.S. is closer to 17 million, including rodents, birds, reptiles, amphibians, and fish. And it is true that animal testing does not necessarily indicate how products will affect humans. The Times cites a 2000 study in the journal Regulatory Toxicology and Pharmacology, reporting that rodent experiments predict toxicity to humans just 43% of the time. Not very accurate results when better alternatives are available.

Times have changed. No longer are animals viewed as “black boxes,” easy “creatures” to be tested upon, and their deaths studied. It is true that the most tests utilized today have not kept pace with scientific progress. In the past, scientists didn’t understand how chemical testing could sicken an animal or measure the effects upon the animal as a result, but they could certainly see if the animal lived or died from that chemical. This led to the "Lethal Dose, 50%" test, invented in 1927, which is based upon how much of a given toxin will kill half of the animals exposed to it. Until June 2011, this was the test Allergan had to use. Thankfully, progress has allowed Allergan, and hopefully soon, many other companies, to move away from seeing animals as just a means to an end. And that is good news for us all.


One thought on “Product Testing Moves Away from Animals

  1. Lisa says:

    This is great news! Let’s hope common manufacturers of personal care products, household cleaning products, cosmetics, pharmaceuticals, etc. follow Allergan’s lead.

    In the meantime, anyone concerned with whether their everyday products are cruelty free can visit leapingbunny.org to get a list of brands that have pledged to go cruelty free, and if your favorite brand isn’t on there, send a letter and ask them to take the pledge!

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